Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 14/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824089 | 1.00 | PARP1 (0.45) | PARP1GRM2HTR3AKCNH2KDM4E | |
| SCHEMBL9243355 | 0.89 | PARP1 (0.55) | PARP1GRM2HTR3AKCNH2KDM4E | |
| SCHEMBL8824093 | 0.89 | PARP1 (0.55) | PARP1GRM2HTR3AKCNH2KDM4E | |
| SCHEMBL8823991 | 0.88 | PARP1 (0.58) | PARP1GRM2HTR3AKCNH2KDM4E | |
| SCHEMBL8823994 | 0.88 | PARP1 (0.58) | PARP1GRM2HTR3AKCNH2KDM4E | |
| SCHEMBL8824085 | 0.85 | PARP1 (0.47) | PARP1GRM2HTR3AKCNH2KDM4E | |
| SCHEMBL8824082 | 0.85 | PARP1 (0.47) | PARP1GRM2HTR3AKCNH2KDM4E | |
| SCHEMBL8824037 | 0.83 | PARP1 (0.42) | PARP1GRM2HTR3AKCNH2KDM4E | |
| SCHEMBL8824032 | 0.83 | PARP1 (0.42) | PARP1GRM2HTR3AKCNH2KDM4E | |
| SCHEMBL9036918 | 0.79 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643920-A | PYRROLO(3,2,1-IJ)QUINOLINES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0638570-A1 | TRICYCLIC COMPOUND HAVING ANTIALLERGIC EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |