Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9734759 | 0.96 | TSHR (0.56) | ALOX15TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL9735618 | 0.95 | ALOX15 (0.47) | ALOX15TSHRHSD17B10KDM4EALDH1A1 | |
| Maleic Acid SCHEMBL8824254 | 0.93 | ALOX15 (0.45) | ALOX15TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL9734807 | 0.88 | GAA (0.46) | ALOX15TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL8824284 | 0.88 | KDM1A (0.41) | ALOX15TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL9735768 | 0.87 | GAA (0.49) | TSHRKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9735396 | 0.87 | GAA (0.51) | ALOX15TSHRHSD17B10ALDH1A1LMNA | |
| Fumaric Acid SCHEMBL9735616 | 0.87 | TSHR (0.46) | ALOX15TSHRHSD17B10KDM4EALDH1A1 | |
| Fumaric Acid SCHEMBL9735611 | 0.87 | TSHR (0.46) | ALOX15TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL597029 | 0.87 | NAMPT (0.46) | TSHRSMN1; SMN2POLBNAMPTTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | claimed |
| US-5652249-A | ADMINISTERING PYROGLUTAMIDE DERIVATIVE | NIPPON SHINYAKU CO., INC. (JP) | 1997-07-29 | — | — | US | disclosed |
| EP-0711554-A1 | ANTIDEPRESSANT | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5102882-A | Nootropic agents | NIPPON SHINYAKU CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |