Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | IL2 | P60568 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824308 | 0.88 | HRH3 (0.43) | HRH3KDM4ELMNAMAPTCYP19A1 | |
| SCHEMBL8824306 | 0.88 | HRH3 (0.46) | HRH3KDM4ELMNAMAPTHTT | |
| SCHEMBL8824282 | 0.83 | HRH3 (0.43) | HRH3KDM4ELMNAMAPTHTT | |
| SCHEMBL1996001 | 0.80 | KDM4E (0.51) | HRH3KDM4ELMNAMAPTHTT | |
| SCHEMBL8824283 | 0.79 | KDM4E (0.46) | HRH3KDM4ELMNAMAPTHTT | |
| SCHEMBL3508886 | 0.78 | KDM4E (0.42) | HRH3KDM4ELMNAMAPTHTT | |
| SCHEMBL6587925 | 0.77 | HRH3 (0.54) | HRH3KDM4ELMNAMAPTHTT | |
| SCHEMBL8443277 | 0.76 | CYP1A1 (0.56) | HRH3KDM4ELMNAMAPTHTT | |
| SCHEMBL471881 | 0.75 | KDM4E (0.62) | HRH3KDM4ELMNAMAPTHTT | |
| SCHEMBL20410843 | 0.72 | KDM4E (0.59) | HRH3KDM4ELMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612474-A | ANTIBODIES AND IMMUNOLOGY | ELI LILLY AND COMPANY (US) | 1997-03-18 | — | — | US | disclosed |