Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.50 |
| ▸ | CDC25B | P30305 | 8/20 | 0.50 |
| ▸ | SELP | P16109 | 3/20 | 0.50 |
| ▸ | VEGFA | P15692 | 2/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998244 | 0.91 | VEGFA (0.48) | SELPVEGFATNF | |
| SCHEMBL12380712 | 0.90 | VEGFA (0.50) | PTPN1CDC25BSELPVEGFAPTPN2 | |
| SCHEMBL12380716 | 0.88 | VEGFA (0.49) | PTPN1CDC25BSELPVEGFAPTPN2 | |
| SCHEMBL6839245 | 0.88 | VEGFA (0.63) | PTPN1CDC25BSELPVEGFATNF | |
| SCHEMBL6930044 | 0.88 | VEGFA (0.63) | PTPN1CDC25BSELPVEGFATNF | |
| SCHEMBL7214255 | 0.88 | VEGFA (0.63) | PTPN1CDC25BSELPVEGFATNF | |
| SCHEMBL6925828 | 0.88 | VEGFA (0.51) | SELPVEGFATNF | |
| SCHEMBL6925831 | 0.88 | VEGFA (0.51) | SELPVEGFATNF | |
| SCHEMBL7933032 | 0.87 | NT5E (0.55) | PTPN1CDC25BSELPPTPN2PTPN6 | |
| SCHEMBL11584750 | 0.87 | NT5E (0.55) | PTPN1CDC25BSELPPTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681829-A | Class of phosphocholine derivatives having antifungal activity | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-10-28 | — | — | US | disclosed |