Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 4/20 | 0.63 |
| ▸ | SELP | P16109 | 8/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930044 | 1.00 | VEGFA (0.63) | VEGFASELPTNFKDM4EDUSP3 | |
| SCHEMBL6839245 | 1.00 | VEGFA (0.63) | VEGFASELPTNFKDM4EDUSP3 | |
| SCHEMBL6925828 | 0.92 | VEGFA (0.51) | VEGFASELPTNFKDM4EDUSP3 | |
| SCHEMBL6925831 | 0.92 | VEGFA (0.51) | VEGFASELPTNFKDM4EDUSP3 | |
| SCHEMBL6927239 | 0.90 | VEGFA (0.64) | VEGFASELPLMNATLR2 | |
| SCHEMBL6831894 | 0.90 | VEGFA (0.64) | VEGFASELPLMNATLR2 | |
| SCHEMBL6925912 | 0.90 | VEGFA (0.64) | VEGFASELPLMNATLR2 | |
| SCHEMBL6838278 | 0.90 | VEGFA (0.64) | VEGFASELPLMNATLR2 | |
| SCHEMBL8824434 | 0.88 | PTPN1 (0.50) | VEGFASELPTNFPTPN1CDC25B | |
| SCHEMBL8998244 | 0.88 | VEGFA (0.48) | VEGFASELPTNFKDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1164140-B1 | NOVEL SULFOFUCOSYLACYLGLYCEROL DERIVATIVES AND UTILIZATION THEREOF AS DRUGS | TOYO SUISAN KAISHA (JP) | 2003-07-09 | — | — | EP | disclosed |
| EP-1164140-A1 | NOVEL SULFOFUCOSYLACYLGLYCEROL DERIVATIVES AND UTILIZATION THEREOF AS DRUGS | Toyo Suisan Kaisha, Ltd. (JP) | 2001-12-19 | — | — | EP | disclosed |