Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23161472 | 0.72 | TDP1 (0.38) | CA12CA1CA2CA9CA14 | |
| SCHEMBL457069 | 0.72 | PTGS1 (0.40) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8824616 | 0.71 | LMNA (0.52) | CA12CA1CA2CA9CA14 | |
| SCHEMBL457070 | 0.71 | PTGS1 (0.49) | CA12CA1CA2CA9CA14 | |
| Silver SCHEMBL11327326 | 0.70 | GAA (0.41) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL11327334 | 0.70 | GAA (0.41) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL359729 | 0.69 | LMNA (0.47) | ALDH1A1HPGDPOLBMAPTALOX12 | |
| SCHEMBL6909820 | 0.69 | SMN1; SMN2 (0.47) | ALDH1A1HPGDPOLBMAPTALOX12 | |
| SCHEMBL6917241 | 0.69 | LMNA (0.47) | ALDH1A1HPGDPOLBMAPTALOX12 | |
| SCHEMBL6917233 | 0.69 | LMNA (0.47) | ALDH1A1HPGDPOLBMAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663379-A | AGROCHEMICAL ACTIVE INGREDIENTS | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |