Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598263 | 0.71 | AKR1B1 (0.44) | AKR1B1CA2CAMK2AGAAKDM4E | |
| SCHEMBL11803971 | 0.71 | AKR1B1 (0.44) | AKR1B1CA2CAMK2AGAAKDM4E | |
| SCHEMBL9637236 | 0.71 | AKR1B1 (0.40) | AKR1B1CA2CAMK2AGAAKDM4E | |
| SCHEMBL11744319 | 0.69 | AKR1B1 (0.42) | AKR1B1CA2CAMK2AGAAKDM4E | |
| SCHEMBL15948192 | 0.69 | AKR1B1 (0.42) | AKR1B1CA2CAMK2AGAAKDM4E | |
| SCHEMBL30940421 | 0.69 | AKR1B1 (0.42) | AKR1B1CA2CAMK2AGAAKDM4E | |
| SCHEMBL12042065 | 0.67 | AKR1B1 (0.41) | AKR1B1GAAKDM4EALDH1A1HPGD | |
| SCHEMBL10404764 | 0.67 | AKR1B1 (0.41) | AKR1B1CA2CAMK2AGAAKDM4E | |
| SCHEMBL5198853 | 0.67 | AKR1B1 (0.52) | AKR1B1CA2CAMK2AGAAKDM4E | |
| SCHEMBL11696665 | 0.67 | AKR1B1 (0.52) | AKR1B1CA2CAMK2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693311-A | Polyiodinated compounds, process for preparing them and diagnostic compositions | GUERBET S.A. (FR) | 1997-12-02 | — | — | US | disclosed |