Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637092 | 0.77 | GPR17 (0.57) | TTRGPR17THRATHRBPOLB | |
| SCHEMBL30502430 | 0.76 | TPMT (0.40) | AKR1B1TTRGPR17THRATHRB | |
| SCHEMBL19678481 | 0.76 | TPMT (0.40) | AKR1B1TTRGPR17THRATHRB | |
| SCHEMBL699224 | 0.74 | TTR (0.50) | AKR1B1TTRTHRATHRBPPARG | |
| SCHEMBL30129029 | 0.73 | AKR1B1 (0.48) | AKR1B1THRATHRBPPARGRXRA | |
| SCHEMBL19678490 | 0.73 | GPR17 (0.36) | TTRGPR17THRATHRBPPARG | |
| SCHEMBL6247495 | 0.73 | LMNA (0.55) | AKR1B1THRATHRBPPARGRXRA | |
| SCHEMBL8824733 | 0.71 | AKR1B1 (0.42) | AKR1B1TPMTKDM4EPOLBHPGD | |
| SCHEMBL18242830 | 0.71 | TTR (0.43) | TTRGPR17ERN1 | |
| SCHEMBL8462416 | 0.70 | AKR1B1 (0.33) | AKR1B1TTRGPR17THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5160725-A | Contrast agent for diagnostic imaging, polyethylene glycol phosphates and carboxylates as stabilizers | SILICA GEL GESELLSCHAFT MBH ADSORPTIONS-TECHNIK, APPARATEBAU (DE) | 1992-11-03 | — | — | US | claimed |
| EP-0284549-B1 | MAGNETIC FLUID COMPOSITIONS | Silica Gel Ges.mbH Absorptionstechnik, Apparatebau (DE) | 1992-07-15 | — | — | EP | claimed |
| US-5160725-A | Contrast agent for diagnostic imaging, polyethylene glycol phosphates and carboxylates as stabilizers | SILICA GEL GESELLSCHAFT MBH ADSORPTIONS-TECHNIK, APPARATEBAU (DE) | 1992-11-03 | — | — | US | disclosed |