Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 12/20 | 0.44 |
| ▸ | PPARA | Q07869 | 12/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824918 | 0.94 | KDR (0.44) | KDRPPARGPPARAFFAR1MAPT | |
| SCHEMBL8825060 | 0.90 | PPARG (0.42) | KDRPPARGPPARAFFAR1 | |
| SCHEMBL8825123 | 0.89 | PPARG (0.38) | KDRPPARGPPARAFFAR1 | |
| SCHEMBL8825042 | 0.88 | PPARD (0.45) | PPARGPPARAFFAR1 | |
| SCHEMBL8824919 | 0.88 | JAK1 (0.33) | PPARGPPARA | |
| SCHEMBL8825034 | 0.86 | TP53 (0.32) | PPARGPPARAFFAR1MAPT | |
| SCHEMBL8825008 | 0.85 | PPARD (0.38) | PPARGPPARA | |
| SCHEMBL8824950 | 0.83 | MEN1 (0.41) | PPARGFFAR1 | |
| SCHEMBL8824985 | 0.82 | ACHE (0.39) | — | |
| SCHEMBL8824961 | 0.81 | PPARD (0.35) | PPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693651-A | HYPOGLYCEMIC AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |