Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 17/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | PDE5A | O76074 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864882 | 0.87 | ABCG2 (0.73) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL1083549 | 0.78 | ABCG2 (0.66) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL14262925 | 0.77 | ABCG2 (0.73) | ABCG2MAPTTP53LMNASMN1; SMN2 | |
| SCHEMBL4866867 | 0.76 | ABCG2 (0.63) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL1063103 | 0.76 | ABCG2 (1.00) | ABCG2MAPTTP53LMNAABCB1 | |
| SCHEMBL8095812 | 0.75 | ABCG2 (1.00) | ABCG2MAPTTP53LMNAABCB1 | |
| SCHEMBL1063729 | 0.75 | PDE4B (0.71) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL13316097 | 0.75 | ABCG2 (0.55) | ABCG2MAPTTP53LMNAABCB1 | |
| SCHEMBL4868573 | 0.75 | ABCG2 (1.00) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL22201447 | 0.75 | HPGD (0.70) | ABCG2MAPTLMNAABCB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040499-A2 | METABOLIC INHIBITORS | SURFACE LOGIX, INC. (US) | 2012-03-29 | — | — | WO | disclosed |