Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17027400 | 1.00 | TSHR (0.40) | TSHRRNPEPSLC7A5CYP19A1LMNA | |
| SCHEMBL23408562 | 0.80 | TSHR (0.36) | TSHRLMNAMMEACE | |
| SCHEMBL8742085 | 0.80 | RNPEP (0.40) | RNPEPSLC7A5LMNAFOLH1MME | |
| SCHEMBL1979969 | 0.79 | LAP3 (0.46) | RNPEPSLC7A5FOLH1MMELAP3 | |
| SCHEMBL2626595 | 0.78 | MME (0.42) | RNPEPSLC7A5FOLH1MME | |
| SCHEMBL28962638 | 0.78 | TSHR (0.42) | TSHRRNPEPSLC7A5CYP19A1LMNA | |
| SCHEMBL3765857 | 0.78 | TSHR (0.42) | TSHRLMNATDP1HCAR2 | |
| SCHEMBL19525758 | 0.78 | TSHR (0.42) | TSHRRNPEPSLC7A5CYP19A1LMNA | |
| SCHEMBL3420611 | 0.78 | TSHR (0.42) | TSHRLMNA | |
| SCHEMBL7222915 | 0.78 | TSHR (0.42) | TSHRRNPEPSLC7A5CYP19A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040127-A1 | SUBSTITUTED NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2012-03-29 | — | — | WO | disclosed |