Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ILK | Q13418 | 10/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826837 | 0.99 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9AMAPTTDP1NFKB1 | |
| SCHEMBL8826664 | 0.99 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9AMAPTTDP1NFKB1 | |
| SCHEMBL8826755 | 0.98 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9AMAPTTDP1NFKB1 | |
| SCHEMBL8826550 | 0.96 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9AMAPTTDP1NFKB1 | |
| SCHEMBL8827217 | 0.94 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9AMAPTTDP1NFKB1 | |
| SCHEMBL8826408 | 0.93 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9AMAPTTDP1NFKB1 | |
| SCHEMBL8826920 | 0.93 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9AMAPTTDP1NFKB1 | |
| SCHEMBL8826402 | 0.91 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9AMAPTTDP1NFKB1 | |
| SCHEMBL8827125 | 0.90 | PTGS2 (0.39) | SMN1; SMN2RAB9AMAPTTDP1NFKB1 | |
| SCHEMBL8826979 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9AMAPTTDP1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684172-A | REACTING BENZOTHIAZOLYL MORPHOLINYL DISULFIDE WITH A MERCAPTOALKYLALKOXYSILANE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-11-04 | — | — | US | disclosed |