Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 18/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 8/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | SLC5A11 | Q8WWX8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12965051 | 0.83 | SLC5A2 (0.50) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL10292573 | 0.82 | SLC5A1 (0.51) | SLC5A2SLC5A1 | |
| SCHEMBL10328445 | 0.82 | SLC5A1 (0.51) | SLC5A2SLC5A1 | |
| SCHEMBL14215765 | 0.75 | SLC5A2 (0.35) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL13057263 | 0.75 | SLC5A2 (0.41) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL12956970 | 0.75 | SLC5A2 (0.39) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL12797197 | 0.75 | SLC5A2 (0.39) | SLC5A2SLC5A1 | |
| SCHEMBL14215830 | 0.74 | SLC5A2 (0.35) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL9611980 | 0.73 | SLC5A2 (0.38) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL12323556 | 0.72 | SLC5A2 (0.37) | SLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170702-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012040279-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2012-03-29 | — | — | WO | disclosed |
| WO-2011127051-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2011-10-13 | — | — | WO | disclosed |