Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10292573 | 1.00 | SLC5A1 (0.51) | SLC5A1SLC5A2 | |
| SCHEMBL12965051 | 0.85 | SLC5A2 (0.50) | SLC5A1SLC5A2 | |
| SCHEMBL882697 | 0.82 | SLC5A2 (0.37) | SLC5A1SLC5A2 | |
| SCHEMBL12323556 | 0.82 | SLC5A2 (0.37) | SLC5A1SLC5A2 | |
| SCHEMBL13964967 | 0.75 | SLC5A1 (0.37) | SLC5A1SLC5A2 | |
| SCHEMBL12956970 | 0.74 | SLC5A2 (0.39) | SLC5A1SLC5A2 | |
| SCHEMBL12797197 | 0.74 | SLC5A2 (0.39) | SLC5A1SLC5A2 | |
| SCHEMBL14215765 | 0.74 | SLC5A2 (0.35) | SLC5A1SLC5A2 | |
| SCHEMBL13057263 | 0.74 | SLC5A2 (0.41) | SLC5A1SLC5A2 | |
| SCHEMBL14215830 | 0.73 | SLC5A2 (0.35) | SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217156-B2 | Solid forms of (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol and methods of their use | LEXICON PHARMACEUTICALS, INC. (US) | 2012-07-10 | — | — | US | disclosed |
| US-20110218159-A1 | METHODS OF USING INHIBITORS OF SODIUM-GLUCOSE COTRANSPORTERS 1 AND 2 | LEXICON PHARMACEUTICALS, INC. | 2011-09-08 | — | — | US | disclosed |
| EP-2332947-A1 | Solid forms of (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol and methods of their use | Lexicon Pharmaceuticals, Inc. (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010009197-A1 | SOLID FORMS OF (2S,3R,4R,5S,6R)-2-(4-CHLORO-3-(4-ETHOXYBENZYL)PHENYL)-6-(METHYLTHIO)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL AND METHODS OF THEIR USE | LEXICON PHARMACEUTICALS, INC. (US) | 2010-01-21 | — | — | WO | disclosed |
| US-20100016422-A1 | SOLID FORMS OF (2S,3R,4R,5S,6R)-2-(4-CHLORO-3-(4-ETHOXYBENZYL)PHENYL)-6-(METHYLTHIO)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL AND METHODS OF THEIR USE | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016422-A1 | SOLID FORMS OF (2S,3R,4R,5S,6R)-2-(4-CHLORO-3-(4-ETHOXYBENZYL)PHENYL)-6-(METHYLTHIO)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL AND METHODS OF THEIR USE | TPMT, PYGL, PNPO | SLC5A1 354/4885SLC5A2 233/4885 |
| US-20110218159-A1 | METHODS OF USING INHIBITORS OF SODIUM-GLUCOSE COTRANSPORTERS 1 AND 2 | SLC5A2, SLC5A1, SLC2A2 | SLC5A1 2/4885SLC5A2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.