⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1623092 | 0.77 | APEX1 (0.33) | — | |
| SCHEMBL8520452 | 0.76 | SLC22A6 (0.30) | — | |
| SCHEMBL2114534 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL9067072 | 0.73 | PTGS1 (0.32) | — | |
| SCHEMBL3311518 | 0.72 | APEX1 (0.32) | — | |
| SCHEMBL5969152 | 0.71 | TSHR (0.38) | — | |
| Ammonia Solution, Strong SCHEMBL8444187 | 0.70 | APEX1 (0.31) | — | |
| SCHEMBL16193609 | 0.70 | MGAM (0.38) | — | |
| SCHEMBL2871424 | 0.70 | GRIK1 (0.31) | — | |
| SCHEMBL1839680 | 0.70 | GRIK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5660847-A | Implantable delivery dispenser comprising exit port | ALZA CORPORATION (US) | 1997-08-26 | — | — | US | disclosed |
| EP-0491803-B1 | IMPLANTABLE DELIVERY DISPENSER | ALZA CORP (US) | 1994-07-20 | — | — | EP | disclosed |
| EP-0491803-A1 | IMPLANTABLE DELIVERY DISPENSER. | ALZA CORP (US) | 1992-07-01 | — | — | EP | disclosed |
| US-5112614-A | IMPLANTABLE DELIVERY DISPENSER | ALZA CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |
| WO-1991004016-A1 | IMPLANTABLE DELIVERY DISPENSER | ALZA CORPORATION (US) | 1991-04-04 | — | — | WO | disclosed |