SCHEMBL1839680

SCHEMBL1839680

CC(=CC(C)CO)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.31
GRIA2 P42262 2/20 0.31
GRIA4 P48058 2/20 0.31
GRIK3 Q13003 2/20 0.31
GRIK5 Q16478 2/20 0.31
GRIA1 P42261 1/20 0.31
GRIK2 Q13002 1/20 0.31
PTGS1 P23219 1/20 0.31
AKR1C3 P42330 1/20 0.31
TSHR P16473 2/20 0.30
APEX1 P27695 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2871424 1.00 GRIK1 (0.31) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL3880960 0.82 ALDH1A1 (0.33)
SCHEMBL3880964 0.82 ALDH1A1 (0.33)
SCHEMBL28995143 0.81 LMNA (0.30)
SCHEMBL30478834 0.81 TSHR (0.36) TSHR
SCHEMBL74357 0.81 GRIK1 (0.31) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL74358 0.81 GRIK1 (0.31) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL30478836 0.80 TSHR (0.35) TSHR
SCHEMBL30826555 0.79 SLC22A6 (0.35) GRIK1GRIA2GRIA4GRIK3GRIK5
SCHEMBL4929051 0.79 RNPEP (0.38) GRIK1GRIA2GRIA4GRIK3GRIK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents CIS BIOPHARMA AG (CH) 2026-02-24 US claimed
US-20220409737-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CIS BIOPHARMA AG (CH) 2022-12-29 US claimed
EP-4051320-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CIS Pharma AG (CH) 2022-09-07 EP claimed
CN-114641316-A Biocompatible polymeric drug carriers for delivery of active agents CIS制药股份公司 2022-06-17 CN claimed
WO-2021084087-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CIS PHARMA AG (CH) 2021-05-06 WO claimed
EP-3071310-B1 PROCESS ADDITIVE FORMULATION AND METHOD FOR FOAM REDUCTION AND/OR FOR INCREASING DRAINAGE KEMIRA OYJ (FI) 2021-05-05 EP claimed
US-9382434-B2 Actinic radiation-curable inkjet ink and image forming method using same Konica Minolta, Inc. (JP) 2016-07-05 US claimed
EP-0521453-B1 Polymeric vehicle for coatings UNIV NORTH DAKOTA (US) 1996-06-05 EP claimed
EP-0431494-B1 Filtration media with low protein adsorbability PALL CORP (US) 1996-02-07 EP claimed
EP-0361814-B1 Fluid treatment system having low affinity for proteinaceous materials PALL CORP (US) 1995-11-15 EP claimed
EP-0254799-A1 (Meth)acrylic ester modified organopolysiloxanes, process for making them and their use as adhesive coating compositions Th. Goldschmidt AG (DE) 1988-02-03 EP claimed
US-20260055182-A1 ANTI-L1-CAM ANTIBODIES AND THEIR USES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS CIS BIOPHARMA AG (CH) 2026-02-26 US disclosed
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents CIS BIOPHARMA AG (CH) 2026-02-24 US disclosed
EP-4615580-A1 ANTI-L1-CAM ANTIBODIES AND THEIR USES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS CIS Biopharma AG (CH) 2025-09-17 EP disclosed
WO-2024100200-A1 ANTI-L1-CAM ANTIBODIES AND THEIR USES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS CIS PHARMA AG (CH) 2024-05-16 WO disclosed
US-4046720-A ACRYLAMIDE MONOMER; CHROMATOGRAPHY CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1977-09-06 US disclosed
US-4035316-A HYDROXY- OR AMINE-SUBSTITUTED ACRYLIC MONOMERS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1977-07-12 US disclosed
US-3993849-A Metal substrate coated with a thermosetting powder coating composition of an acrylic polymer, a hydroxy functional plasticizer and a blocked polyisocyanate cross-linking agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-23 US disclosed
US-3985632-A COPOLYMERIZATION OF AN ACRYLIC MONOMER AND A CROSS-LINKING AGENT IN AN AQUEOUS SOLUBLE POLYMER CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1976-10-12 US disclosed
US-3957741-A CROSSLINKED, POROUS, POLYACRYLATE BEADS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558432-B2 Biocompatible polymeric drug carriers for delivering active agents MSR1, CD47, SLC43A1 GRIK1 3690/4885GRIA2 2435/4885GRIA4 2995/4885
US-20220409737-A1 BIOCOMPATIBLE POLYMERIC DRUG CARRIERS FOR DELIVERING ACTIVE AGENTS CD47, DNPEP, MSR1 GRIK1 4017/4885GRIA2 2612/4885GRIA4 3206/4885
US-20260055182-A1 ANTI-L1-CAM ANTIBODIES AND THEIR USES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS IGSF11, L1CAM, CD74 GRIK1 2429/4885GRIA2 835/4885GRIA4 1275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.