Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 17/20 | 0.41 |
| ▸ | CA2 | P00918 | 17/20 | 0.41 |
| ▸ | CA9 | Q16790 | 15/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA7 | P43166 | 5/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.38 |
| ▸ | CA3 | P07451 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 4/20 | 0.38 |
| ▸ | CA6 | P23280 | 4/20 | 0.38 |
| ▸ | CA5A | P35218 | 4/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351465 | 0.92 | TSHR (0.46) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL575454 | 0.86 | TSHR (0.48) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL575603 | 0.86 | TSHR (0.55) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL14779186 | 0.83 | TSHR (0.52) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL14778767 | 0.83 | TSHR (0.52) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL776829 | 0.81 | CA1 (0.61) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL9543126 | 0.80 | CA1 (0.41) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL8827678 | 0.79 | TSHR (0.42) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL3190035 | 0.79 | CA1 (0.62) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL30164353 | 0.77 | CA1 (0.39) | TSHRKDM4EUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677299-A | VASOPRESSIN OR OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-10-14 | — | — | US | disclosed |
| US-5498609-A | Benzoazepinyl compounds as oxytocin and vasopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |