Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LIPE | Q05469 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10864744 | 0.88 | SGMS2 (0.56) | SGMS2NPC1HTTLIPEGAA | |
| SCHEMBL5046787 | 0.87 | SGMS2 (0.52) | SGMS2NPC1HTTLIPEGAA | |
| SCHEMBL9642440 | 0.87 | SGMS2 (0.59) | SGMS2NPC1HTTLIPEGAA | |
| SCHEMBL1097809 | 0.87 | SGMS2 (0.59) | SGMS2NPC1HTTLIPEGAA | |
| SCHEMBL5046789 | 0.87 | SGMS2 (0.52) | SGMS2NPC1HTTLIPEGAA | |
| SCHEMBL10442994 | 0.87 | SGMS2 (0.52) | SGMS2NPC1HTTLIPEGAA | |
| SCHEMBL9731418 | 0.84 | SGMS2 (0.50) | SGMS2NPC1HTTLIPEGAA | |
| SCHEMBL10346925 | 0.80 | SGMS2 (0.62) | SGMS2NPC1HTTGAAPTGER1 | |
| SCHEMBL30468871 | 0.80 | SGMS2 (0.67) | SGMS2NPC1HTTGAAPTGER1 | |
| SCHEMBL71081 | 0.80 | SGMS2 (0.67) | SGMS2NPC1HTTGAAPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633256-A | Certain pyrimidinyloxy-phenyl acrylates, derivatives thereof and their fungicidal use | ZENECA LIMITED (GB) | 1997-05-27 | — | — | US | disclosed |
| US-5602076-A | INSECTICIDES, NEMATOCIDES | ZENECA LIMITED (GB) | 1997-02-11 | — | — | US | disclosed |
| US-5470819-A | Plant growth regulators, insecticides | ZENECA LIMITED (GB) | 1995-11-28 | — | — | US | disclosed |
| EP-0242081-B1 | Fungicides | ZENECA LTD (GB) | 1994-04-27 | — | — | EP | disclosed |
| US-5057146-A | CERTAIN 2-PYRIDYL OXY-PHENYL ACRYLATES HAVING FUNGICIDAL, INSECTICIDAL, NEMATOCIDAL AND PLANT GROWTH REGULATING ACTIVITY | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-15 | — | — | US | disclosed |
| EP-0391451-A1 | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-10 | — | — | EP | disclosed |
| EP-0387923-A2 | Fungicides | ZENECA LIMITED (GB) | 1990-09-19 | — | — | EP | disclosed |
| EP-0242081-A1 | Fungicides | ZENECA LIMITED (GB) | 1987-10-21 | — | — | EP | disclosed |