Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 12/20 | 1.00 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.67 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882809 | 0.83 | F2R (1.00) | F2R | |
| SCHEMBL23367946 | 0.82 | F2R (0.70) | F2RKCNK3KCNK9PTGS1RXFP1 | |
| SCHEMBL882772 | 0.82 | F2R (1.00) | F2RKCNK3KCNK9RXFP1 | |
| SCHEMBL882806 | 0.82 | F2R (1.00) | F2RKCNK3KCNK9 | |
| SCHEMBL882721 | 0.82 | F2R (1.00) | F2R | |
| SCHEMBL882797 | 0.81 | F2R (1.00) | F2RKCNK3KCNK9 | |
| SCHEMBL882467 | 0.81 | F2R (1.00) | F2R | |
| SCHEMBL29766853 | 0.81 | F2R (1.00) | F2R | |
| SCHEMBL12764065 | 0.80 | KCNK3 (0.83) | F2RKCNK3KCNK9PTGS1RXFP1 | |
| SCHEMBL16553649 | 0.80 | KCNK3 (0.70) | F2RKCNK3KCNK9PTGS1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422262-B2 | Compounds and methods for treating diseases mediated by protease activated receptors | THE BROAD INSTITUTE, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| US-9422262-B2 | Compounds and methods for treating diseases mediated by protease activated receptors | THE BROAD INSTITUTE, INC. (US) | 2016-08-23 | — | — | US | disclosed |
| WO-2012040636-A2 | COMPOUNDS AND METHODS FOR TREATING DISEASES MEDIATED BY PROTEASE ACTIVATED RECEPTORS | THE BROAD INSTITUTE, INC. (US) | 2012-03-29 | — | — | WO | disclosed |