Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20345279 | 0.80 | ELANE (0.44) | ELANEATML3MBTL1BCHECHRM2 | |
| SCHEMBL18842482 | 0.75 | ELANE (0.51) | ELANEATML3MBTL1ESR1CA12 | |
| SCHEMBL12999209 | 0.75 | ELANE (0.45) | ELANEATML3MBTL1BCHECHRM2 | |
| SCHEMBL21291493 | 0.73 | ELANE (0.42) | ELANEATML3MBTL1ESR1CA12 | |
| SCHEMBL21505065 | 0.73 | ELANE (0.46) | ELANEATML3MBTL1BCHECHRM2 | |
| SCHEMBL10618820 | 0.71 | ATM (0.68) | ELANEATML3MBTL1ESR1ESR2 | |
| SCHEMBL27054893 | 0.71 | ELANE (0.41) | ELANEATML3MBTL1BCHECHRM2 | |
| SCHEMBL10359066 | 0.70 | ELANE (0.46) | ELANECHRM2ESR1CA12CA1 | |
| SCHEMBL97654 | 0.70 | ELANE (0.46) | ELANECHRM2ESR1CA12CA1 | |
| SCHEMBL10787522 | 0.70 | ESR1 (0.43) | ELANECHRM2ESR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650468-A | Continuous process for grafting a polyolefin, the grafted polyolefins obtained by means of this process | SOLVAY (SOCIETE ANONYME) (BE) | 1997-07-22 | — | — | US | disclosed |