Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873379 | 0.70 | GRIN1 (0.51) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8654398 | 0.69 | GRIN1 (0.52) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8828104 | 0.69 | GRIN1 (0.63) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL29951318 | 0.69 | GRIN1 (0.50) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8828095 | 0.68 | GRIN1 (0.49) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8872432 | 0.66 | PARP1 (0.53) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8828081 | 0.66 | GRIN1 (0.46) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8828099 | 0.65 | KMT2A (0.32) | ALDH1A1 | |
| Phosphonic Acid SCHEMBL27504235 | 0.64 | GRIN1 (0.60) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL29531428 | 0.63 | GRIN1 (1.00) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646132-A | TREATING CEREBRAL ISCHEMIA | ADIR ET COMPAGNIE (FR) | 1997-07-08 | — | — | US | disclosed |
| US-5536709-A | INHIBITORS OF HYPERACTIVATION OF EXCITATORY AMINO ACIDS | ADIR ET COMPAGNIE (FR) | 1996-07-16 | — | — | US | disclosed |