Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828092 | 0.72 | MMP1 (0.36) | KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL8637396 | 0.72 | PTGES (0.36) | — | |
| SCHEMBL8828082 | 0.65 | GRIN1 (0.45) | ALDH1A1 | |
| SCHEMBL8612392 | 0.61 | NR4A2 (0.33) | ALDH1A1 | |
| SCHEMBL8872967 | 0.59 | TSHR (0.40) | KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL5973965 | 0.59 | HRH4 (0.33) | KMT2APDCD1LG2CD274MEN1 | |
| SCHEMBL7675179 | 0.59 | HRH4 (0.56) | KMT2AMEN1 | |
| SCHEMBL17372703 | 0.59 | GLP1R (0.48) | CYP1A2ALDH1A1HPGDNPSR1 | |
| SCHEMBL8071245 | 0.58 | CRHR1 (0.35) | ALDH1A1 | |
| SCHEMBL8078338 | 0.58 | PDE4A (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646132-A | TREATING CEREBRAL ISCHEMIA | ADIR ET COMPAGNIE (FR) | 1997-07-08 | — | — | US | disclosed |
| US-5536709-A | INHIBITORS OF HYPERACTIVATION OF EXCITATORY AMINO ACIDS | ADIR ET COMPAGNIE (FR) | 1996-07-16 | — | — | US | disclosed |