Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828255 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL8745922 | 0.88 | KCNA5 (0.38) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL8745936 | 0.86 | KCNA5 (0.35) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL8745918 | 0.85 | HRH1 (0.35) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL8828382 | 0.85 | CYP1A2 (0.36) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL8745960 | 0.74 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL8828387 | 0.70 | EPHX1 (0.42) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL28199354 | 0.69 | HTT (0.46) | ALDH1A1CYP3A4CYP2C19GAA | |
| SCHEMBL28213057 | 0.67 | TSHR (0.42) | KDM4EMEN1KMT2AVNN1ALDH1A1 | |
| SCHEMBL8753243 | 0.67 | HSPA5 (0.52) | SMN1; SMN2VNN1ALDH1A1CYP1A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672567-A | PRE- AND POST-EMERGENCE | ZENECA LIMITED (GB) | 1997-09-30 | — | — | US | disclosed |
| US-5670453-A | PYRAZINEARYL COMPOUND | ZENECA LIMITED (GB) | 1997-09-23 | — | — | US | disclosed |
| WO-1995029898-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |