Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828382 | 0.86 | CYP1A2 (0.36) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL8828262 | 0.85 | SMN1; SMN2 (0.37) | MEN1KMT2AKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL8828255 | 0.82 | SMN1; SMN2 (0.38) | MEN1KMT2AKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL8745922 | 0.80 | KCNA5 (0.38) | MEN1KMT2AKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL8745936 | 0.78 | KCNA5 (0.35) | MEN1KMT2AKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL8745965 | 0.78 | HRH1 (0.37) | HRH1CYP2D6CHRM1HTR2AKCNH2 | |
| SCHEMBL8745917 | 0.67 | HPGD (0.41) | KDM4EGAACYP3A4 | |
| SCHEMBL8550005 | 0.67 | NPC1 (0.34) | POLBCYP3A4 | |
| SCHEMBL28213057 | 0.66 | TSHR (0.42) | MEN1KMT2AKDM4EVNN1ALDH1A1 | |
| SCHEMBL28544303 | 0.66 | HTT (0.44) | HRH1CYP2D6CHRM1HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672567-A | PRE- AND POST-EMERGENCE | ZENECA LIMITED (GB) | 1997-09-30 | — | — | US | disclosed |
| US-5670453-A | PYRAZINEARYL COMPOUND | ZENECA LIMITED (GB) | 1997-09-23 | — | — | US | disclosed |
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029898-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |