Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | ADH5 | P11766 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828392 | 1.00 | TBXAS1 (0.41) | TBXAS1ADH5CYP3A4BAZ2BMAOB | |
| SCHEMBL11015694 | 0.81 | TBXAS1 (0.44) | TBXAS1ADH5CYP3A4BAZ2BMAOB | |
| SCHEMBL11015693 | 0.81 | TBXAS1 (0.44) | TBXAS1ADH5CYP3A4BAZ2BMAOB | |
| SCHEMBL8828266 | 0.77 | MAOB (0.54) | TBXAS1ADH5CYP3A4BAZ2BMAOB | |
| SCHEMBL8828261 | 0.77 | MAOB (0.54) | TBXAS1ADH5CYP3A4BAZ2BMAOB | |
| SCHEMBL8828222 | 0.75 | IDO1 (0.50) | TBXAS1ADH5CYP3A4MAOBCYP11B1 | |
| SCHEMBL8828227 | 0.75 | IDO1 (0.50) | TBXAS1ADH5CYP3A4MAOBCYP11B1 | |
| SCHEMBL10365507 | 0.75 | IDO1 (0.44) | ADH5CYP3A4BAZ2BENPP2MKNK1 | |
| SCHEMBL8828161 | 0.75 | TBXAS1 (0.39) | TBXAS1ADH5CYP3A4BAZ2BMAOB | |
| SCHEMBL8828171 | 0.75 | TBXAS1 (0.39) | TBXAS1ADH5CYP3A4BAZ2BMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607953-A | ANTIISCHEMIC AGENTS | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0344577-B1 | Butenoic or propenoic acid derivatives | EISAI CO LTD (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5382595-A | Antiischemic agents | EISAI CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0344577-A2 | Butenoic or propenoic acid derivatives | Eisai Co., Ltd. (JP) | 1989-12-06 | — | — | EP | disclosed |