Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 9/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 9/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882625 | 0.96 | TBXAS1 (0.48) | TBXAS1CYP2C19CYP4F2CYP4A11CPB2 | |
| SCHEMBL882626 | 0.92 | TBXAS1 (0.40) | TBXAS1CYP2C19CYP4F2CYP4A11CPB2 | |
| SCHEMBL10081564 | 0.92 | TBXAS1 (0.40) | TBXAS1CYP2C19CYP4F2CYP4A11CPB2 | |
| SCHEMBL882735 | 0.92 | TBXAS1 (0.40) | TBXAS1CYP2C19CYP4F2CYP4A11CPB2 | |
| SCHEMBL798439 | 0.89 | TBXAS1 (0.50) | TBXAS1CYP2C19CYP4F2CYP4A11CPB2 | |
| SCHEMBL9182194 | 0.85 | TBXAS1 (0.54) | TBXAS1CYP2C19CYP4F2CYP4A11CPB2 | |
| SCHEMBL798202 | 0.85 | TBXAS1 (0.54) | TBXAS1CYP2C19CYP4F2CYP4A11CPB2 | |
| SCHEMBL9177719 | 0.83 | CYP2C19 (0.58) | TBXAS1CYP2C19CYP4F2CYP4A11CPB2 | |
| SCHEMBL9182262 | 0.83 | CYP2C19 (0.58) | TBXAS1CYP2C19CYP4F2CYP4A11CPB2 | |
| SCHEMBL9181319 | 0.83 | CYP2C19 (0.56) | TBXAS1CYP2C19CYP4F2CYP4A11CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040177-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF DIABETES AND DYSLIPIDEMIA | KAREUS THERAPEUTICS, SA (CH) | 2012-03-29 | — | — | WO | disclosed |