Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 14/20 | 0.64 |
| ▸ | TACR1 | P25103 | 3/20 | 0.63 |
| ▸ | TACR3 | P29371 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL8940484 | 0.94 | TACR2 (0.58) | TACR2TACR1TACR3 | |
| SCHEMBL8828883 | 0.91 | TACR2 (0.64) | TACR2TACR1 | |
| SCHEMBL8828888 | 0.90 | TACR2 (0.66) | TACR2TACR1 | |
| SCHEMBL8301195 | 0.90 | TACR2 (0.69) | TACR2TACR1TACR3 | |
| SCHEMBL8828884 | 0.90 | TACR2 (0.69) | TACR2TACR1TACR3 | |
| SCHEMBL4609381 | 0.86 | TACR2 (0.75) | TACR2TACR1 | |
| SCHEMBL14434385 | 0.86 | TACR2 (0.75) | TACR2TACR1 | |
| Citric Acid SCHEMBL8940494 | 0.85 | TACR2 (0.58) | TACR2TACR1 | |
| Citric Acid SCHEMBL9255586 | 0.84 | TACR2 (0.58) | TACR2TACR1 | |
| Citric Acid SCHEMBL8940461 | 0.84 | TACR2 (0.62) | TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677317-A | Lactam compounds which are useful in the treatment of asthma | ZENECA LIMITED (GB) | 1997-10-14 | — | — | US | claimed |