SCHEMBL8829324

SCHEMBL8829324

NCCCCCC(N)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.57
HTR2A P28223 2/20 0.57
SLC7A5 Q01650 7/20 0.45
MAOA P21397 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
SCN4A P35499 2/20 0.42
SLC2A1 P11166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9189348 0.98 HRH1 (0.59) HRH1HTR2ASLC7A5MAOATAAR1
Iodide SCHEMBL28187143 0.96 HRH1 (0.57) HRH1HTR2ASLC7A5MAOATAAR1
SCHEMBL3634229 0.91 HRH1 (0.68) HRH1HTR2AMAOATAAR1SCN4A
SCHEMBL17373052 0.89 SCN4A (0.50) HRH1HTR2ATAAR1SCN4ASLC2A1
Hydrochloric Acid SCHEMBL28350804 0.87 SCN4A (0.48) HRH1HTR2ATAAR1SCN4ASLC2A1
SCHEMBL29217898 0.86 CHRNB2 (0.50) HRH1HTR2ASLC7A5MAOATAAR1
SCHEMBL4672036 0.84 HRH1 (0.68) HRH1HTR2ATAAR1SCN4A
SCHEMBL4672537 0.84 HRH1 (0.68) HRH1HTR2ATAAR1SCN4A
SCHEMBL4679643 0.84 HRH1 (0.68) HRH1HTR2ATAAR1SCN4A
SCHEMBL21098991 0.83 HRH1 (0.47) HRH1HTR2ATAAR1SCN4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5679841-A USING A HYDROPHOBIC SOLVENT PHASE AND AN AQUEOUS PHASE CONTAINING A STRONG ACID AND AN AUXILIARY AMINE; NEUTRALIZATION OF AQUEOUS PHASE BAYER AKTIENGESELLSCHAFT (DE) 1997-10-21 US disclosed
US-5648520-A DISTILLATION, SOLVENT EXTRACTION BAYER AKTIENGESELLSCHAFT (DE) 1997-07-15 US disclosed