Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753645 | 0.84 | TDP1 (0.31) | TDP1USP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL28914556 | 0.84 | TDP1 (0.31) | TDP1USP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL30151172 | 0.84 | TDP1 (0.31) | TDP1USP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL30346502 | 0.84 | TDP1 (0.31) | TDP1USP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL30346501 | 0.84 | TDP1 (0.31) | TDP1USP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL30346659 | 0.84 | TDP1 (0.31) | TDP1USP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL7043955 | 0.76 | — | — | |
| SCHEMBL30763279 | 0.76 | TDP1 (0.33) | TDP1ALDH1A1 | |
| SCHEMBL28403501 | 0.76 | TDP1 (0.33) | TDP1ALDH1A1 | |
| SCHEMBL28557963 | 0.75 | USP2 (0.33) | TDP1USP2ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668271-A | Indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| US-5591842-A | ANTICARCINOGENIC AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| US-5589365-A | ANTITUMOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0545195-B1 | Indolopyrrolocarbazole derivatives | BANYU PHARMA CO LTD (JP) | 1995-11-22 | — | — | EP | disclosed |
| WO-1993011145-A1 | INDOLOPYRROLOCARBAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |
| EP-0545195-A1 | Indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |