Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541344 | 0.94 | LOXL2 (0.47) | LOXL2CHRM2IDO1CA1CA2 | |
| SCHEMBL17848993 | 0.88 | LOXL2 (0.44) | LOXL2CHRM2IDO1CA1CA2 | |
| SCHEMBL4092879 | 0.87 | LOXL2 (0.49) | LOXL2CHRM2IDO1CA1CA2 | |
| SCHEMBL6523856 | 0.87 | LOXL2 (0.49) | LOXL2CHRM2IDO1CA1CA2 | |
| SCHEMBL4104161 | 0.87 | LOXL2 (0.49) | LOXL2CHRM2IDO1CA1CA2 | |
| Hydrochloric Acid SCHEMBL2511528 | 0.85 | LOXL2 (0.47) | LOXL2CHRM2IDO1CA1CA2 | |
| Hydrochloric Acid SCHEMBL2511527 | 0.85 | LOXL2 (0.47) | LOXL2CHRM2IDO1CA1CA2 | |
| SCHEMBL5099679 | 0.85 | LOXL2 (0.47) | LOXL2CHRM2IDO1LMNAMC4R | |
| Hydrochloric Acid SCHEMBL5096882 | 0.84 | LOXL2 (0.46) | LOXL2CHRM2IDO1LMNAMC4R | |
| SCHEMBL12793699 | 0.81 | CHRM2 (0.49) | LOXL2CHRM2IDO1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650134-A | Peptides | NOVARTIS AG (FORMERLY SANDOZ LTD.) (CH) | 1997-07-22 | — | — | US | disclosed |
| EP-0607103-A2 | Somatostatin analogs containing chelating groups and their radiolabeled compositions | SANDOZ LTD. (CH) | 1994-07-20 | — | — | EP | disclosed |