Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.43 |
| ▸ | ALOX15B | O15296 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9441377 | 0.81 | CYP3A4 (0.48) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2085218 | 0.81 | ATM (0.48) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3561638 | 0.81 | CYP3A4 (0.42) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28763247 | 0.81 | CYP3A4 (0.42) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9441512 | 0.75 | CYP3A4 (0.42) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL15758608 | 0.74 | PLA2G4A (0.47) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL15758610 | 0.74 | PLA2G4A (0.47) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2336960 | 0.74 | CYP3A4 (0.69) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL28378980 | 0.72 | CYP3A4 (0.67) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL27290504 | 0.72 | CYP3A4 (0.67) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670526-A | ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |