Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL883035 | 1.00 | SLC1A2 (0.38) | SLC1A2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL2428831 | 1.00 | SLC1A2 (0.38) | SLC1A2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL2976643 | 1.00 | SLC1A2 (0.38) | SLC1A2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL19144063 | 1.00 | SLC1A2 (0.38) | SLC1A2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL16277957 | 0.88 | MEN1 (0.41) | CHRM2CHRM4CHRM3MEN1BLM | |
| SCHEMBL16277959 | 0.88 | MEN1 (0.41) | CHRM2CHRM4CHRM3MEN1BLM | |
| Hydrochloric Acid SCHEMBL15174055 | 0.86 | MEN1 (0.40) | CHRM2CHRM4CHRM3ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL15174054 | 0.86 | MEN1 (0.40) | CHRM2CHRM4CHRM3ALDH1A1MEN1 | |
| SCHEMBL24039255 | 0.80 | MAPK1 (0.37) | SLC1A2CHRM2CHRM3 | |
| SCHEMBL28948795 | 0.80 | CHRNB2 (0.40) | SLC1A2CHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040242-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-03-29 | — | — | WO | disclosed |