Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13864102 | 0.80 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4802643 | 0.79 | TSHR (0.49) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL9565660 | 0.77 | ALDH1A1 (0.37) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL13864091 | 0.74 | TSHR (0.49) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4805790 | 0.74 | TSHR (0.42) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4810528 | 0.72 | TSHR (0.41) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL4809586 | 0.72 | TSHR (0.41) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL15467643 | 0.71 | TSHR (0.64) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL12577486 | 0.71 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| Acrylic Acid SCHEMBL5014743 | 0.71 | TSHR (0.64) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658629-A | BASE LAYER HAVING ONE SIDE IMPERVIOUS TO WATER VAPOR AND SILICONE MIGRATION AND SECOND SIDE PERMEABLE TO WATER VAPOR | MORGAN ADHESIVES COMPANY (US) | 1997-08-19 | — | — | US | disclosed |