Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CFD | P00746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330589 | 0.90 | KDM4E (0.57) | MAPTHTTKMT2ABACE1POLB | |
| SCHEMBL805920 | 0.87 | KDM4E (0.58) | MAPTHTTNPSR1KMT2ABACE1 | |
| SCHEMBL27792264 | 0.86 | MAPT (0.67) | MAPTHTTNPSR1KMT2ABACE1 | |
| SCHEMBL27946281 | 0.86 | MAPT (0.64) | MAPTHTTNPSR1KMT2ABACE1 | |
| SCHEMBL24001 | 0.86 | MAPT (0.66) | MAPTHTTNPSR1KMT2APOLB | |
| SCHEMBL1318999 | 0.85 | CFD (0.67) | MAPTHTTNPSR1KMT2ABACE1 | |
| SCHEMBL8897950 | 0.81 | MAPT (0.49) | MAPTHTTNPSR1KMT2ABACE1 | |
| SCHEMBL11793587 | 0.80 | BACE1 (0.61) | MAPTHTTNPSR1KMT2ABACE1 | |
| SCHEMBL3382142 | 0.79 | CFD (0.54) | MAPTALDH1A1CFDLMNASMN1; SMN2 | |
| SCHEMBL12950694 | 0.79 | BACE1 (0.56) | MAPTHTTNPSR1KMT2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661153-A | FOR TREATING ALLERGIES, ASTHMA, DERMATITIS, GRAFT REJECTIONS | JAPAN ENERGY CORPORATION (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0700908-A1 | 1-Arylpyrimidine derivatives and pharmaceutical use thereof | JAPAN ENERGY CORPORATION (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-4024160-A | Substituted 2-amino chromones and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1977-05-17 | — | — | US | disclosed |
| US-3932466-A | Substituted 2-amino chromones and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1976-01-13 | — | — | US | disclosed |