Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 8/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831336 | 0.91 | VDR (0.54) | VDRHDAC3HDAC6 | |
| SCHEMBL8831420 | 0.90 | VDR (0.65) | VDR | |
| SCHEMBL8831233 | 0.89 | VDR (0.54) | VDR | |
| SCHEMBL8831220 | 0.86 | VDR (0.55) | VDRHDAC3HDAC6 | |
| SCHEMBL9064287 | 0.86 | VDR (0.65) | VDR | |
| SCHEMBL8831308 | 0.82 | VDR (0.55) | VDRHDAC3HDAC6 | |
| SCHEMBL3218414 | 0.80 | VDR (0.71) | VDRHDAC6 | |
| SCHEMBL13392358 | 0.80 | VDR (0.71) | VDRHDAC6 | |
| SCHEMBL13392725 | 0.80 | VDR (0.71) | VDRHDAC6 | |
| SCHEMBL8831315 | 0.80 | VDR (0.52) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647219-B1 | DERIVATIVES IN THE VITAMIN D SERIES MODIFIED AT THE 20 POSITION, A METHOD OF PREPARING SUCH DERIVATIVES, INTERMEDIATES USED IN THIS METHOD, PHARMACEUTICAL PREPARATIONS CONTAINING THE DERIVATIVES AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AG (DE) | 1996-07-31 | — | — | EP | claimed |
| US-5700791-A | TREATMENT OF HYPERPROLIFERATIVE DISEASES OF THE SKIN | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-23 | — | — | US | disclosed |
| US-5585368-A | SKIN DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| EP-0647219-B1 | DERIVATIVES IN THE VITAMIN D SERIES MODIFIED AT THE 20 POSITION, A METHOD OF PREPARING SUCH DERIVATIVES, INTERMEDIATES USED IN THIS METHOD, PHARMACEUTICAL PREPARATIONS CONTAINING THE DERIVATIVES AND THEIR USE IN THE PREPARATION OF DRUGS | SCHERING AG (DE) | 1996-07-31 | — | — | EP | disclosed |