Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 12/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8832131 | 0.99 | KMT2A (0.52) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL8832608 | 0.91 | KMT2A (0.45) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL8832221 | 0.90 | L3MBTL1 (0.48) | KMT2AMEN1NR1I2AHRMAPT | |
| Hydrochloric Acid SCHEMBL8832015 | 0.90 | KMT2A (0.44) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL8832042 | 0.90 | L3MBTL1 (0.48) | KMT2AMEN1NR1I2AHRMAPT | |
| Hydrochloric Acid SCHEMBL8832062 | 0.89 | L3MBTL1 (0.47) | KMT2AMEN1NR1I2AHRMAPT | |
| Hydrochloric Acid SCHEMBL8832230 | 0.89 | L3MBTL1 (0.47) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL9539120 | 0.78 | SLC2A1 (0.39) | KMT2AMEN1MAPTKDM4ECASP1 | |
| SCHEMBL8832632 | 0.78 | L3MBTL1 (0.45) | KMT2AMEN1NR1I2AHRMAPT | |
| SCHEMBL8832552 | 0.77 | KMT2A (0.40) | KMT2AMEN1NR1I2AHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597921-A | ANTITUMOR AGENTS, TREATMENT OF LEUKEMIA | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0695754-A1 | INDOLO 2,3-b]QUINOXALINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-02-07 | — | — | EP | disclosed |