Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832874 | 0.87 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL8832721 | 0.86 | ECE1 (0.31) | SIGMAR1 | |
| SCHEMBL8834015 | 0.81 | CHRM5 (0.35) | SIGMAR1 | |
| SCHEMBL9214070 | 0.81 | CHRM5 (0.35) | SIGMAR1 | |
| SCHEMBL8832516 | 0.79 | — | — | |
| SCHEMBL9542123 | 0.79 | — | — | |
| SCHEMBL8832700 | 0.78 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL8832907 | 0.77 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL27531638 | 0.76 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL8834252 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608056-A | Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| WO-1993021186-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-28 | — | — | WO | disclosed |