Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2322149 | 0.90 | SMN1; SMN2 (0.59) | SMN1; SMN2POLBTDP1MAPTRAB9A | |
| SCHEMBL2324701 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBTDP1MAPTRAB9A | |
| SCHEMBL29066650 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2POLBTDP1MAPTRAB9A | |
| SCHEMBL1888991 | 0.79 | MAPT (0.69) | SMN1; SMN2POLBTDP1MAPTRAB9A | |
| Trifluoroacetic Acid SCHEMBL21640604 | 0.79 | POLB (0.51) | SMN1; SMN2POLBTDP1MAPTRAB9A | |
| SCHEMBL11120338 | 0.78 | NPC1 (0.68) | SMN1; SMN2NPC1EGFR | |
| SCHEMBL1430419 | 0.77 | MAPT (0.67) | SMN1; SMN2TDP1MAPTRAB9ANPC1 | |
| SCHEMBL4110225 | 0.76 | ALDH1A1 (0.72) | POLBTDP1MAPTRAB9ANPC1 | |
| SCHEMBL25667855 | 0.76 | ALDH1A1 (0.55) | SMN1; SMN2RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21640605 | 0.76 | KMT2A (0.48) | SMN1; SMN2POLBTDP1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |