Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834387 | 0.91 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL8833162 | 0.91 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL8834291 | 0.87 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL8833875 | 0.83 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL8833321 | 0.82 | — | — | |
| SCHEMBL8832698 | 0.82 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8834428 | 0.81 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8832686 | 0.79 | — | — | |
| SCHEMBL8833235 | 0.79 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL8834153 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |