Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428406 | 0.85 | HSD17B10 (0.37) | HSD17B10NR1H2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL875744 | 0.74 | HSD17B10 (0.38) | HSD17B10NR1H2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL875743 | 0.74 | HSD17B10 (0.38) | HSD17B10NR1H2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL35211488 | 0.73 | HSD17B10 (0.40) | HSD17B10NR1H2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL17654997 | 0.72 | HSD17B10 (0.42) | HSD17B10NR1H2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL883204 | 0.72 | HSD17B10 (0.42) | HSD17B10NR1H2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL905280 | 0.72 | HSD17B10 (0.42) | HSD17B10NR1H2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL905275 | 0.72 | HSD17B10 (0.42) | HSD17B10NR1H2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL16369976 | 0.72 | HSD17B10 (0.42) | HSD17B10NR1H2SMN1; SMN2CHRM2CHRM1 | |
| SCHEMBL15776522 | 0.72 | HSD17B10 (0.42) | HSD17B10NR1H2SMN1; SMN2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040242-A1 | SUBSTITUTED PROLINE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2012-03-29 | — | — | WO | disclosed |