Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | DNA2 | P51530 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8082547 | 0.86 | TSHR (0.47) | TSHRTDP1L3MBTL1ALDH1A1GPR35 | |
| SCHEMBL28423348 | 0.85 | TSHR (0.58) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5780887 | 0.81 | TDP1 (0.56) | TSHRTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL3671 | 0.78 | TSHR (0.68) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8610738 | 0.78 | TSHR (0.68) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL29471725 | 0.78 | TSHR (0.68) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL30893562 | 0.78 | TSHR (0.68) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL29696138 | 0.77 | TSHR (0.67) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL30727560 | 0.77 | TSHR (0.67) | TSHRTDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL78205 | 0.77 | TSHR (0.67) | TSHRTDP1L3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |