SCHEMBL8833775

SCHEMBL8833775

CCCC1CCC(c2cc(F)c(-c3ccc(OC(F)(F)C(F)C(F)(F)F)c(F)c3)c(F)c2)CC1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.33
RECQL P46063 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
MEN1 O00255 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
PDE2A O00408 1/20 0.30
EPHX2 P34913 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8833748 0.93 GAA (0.32) RECQLMAPT
SCHEMBL8834268 0.92 GAA (0.34) RECQLMAPT
SCHEMBL7914144 0.90 CYP2C9 (0.39) CYP2C9RECQLALDH1A1LMNAMAPT
SCHEMBL7911864 0.89 CYP2C9 (0.39) CYP2C9RECQLALDH1A1LMNAMAPT
SCHEMBL8834624 0.88 CYP2C9 (0.34) CYP2C9RECQLALDH1A1LMNAMAPT
SCHEMBL7903615 0.88 ALDH1A1 (0.36) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL7914004 0.86 CYP2C9 (0.37) CYP2C9RECQLALDH1A1LMNAMAPT
SCHEMBL8834211 0.86 CYP2C9 (0.37) CYP2C9RECQLALDH1A1LMNAMAPT
SCHEMBL7911157 0.86 GRIN2B (0.33) RECQLMAPTMEN1KMT2AEPHX2
SCHEMBL7911228 0.85 GRIN2B (0.35) RECQLMAPTMEN1KMT2APDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640578-B1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition CHISSO CORP (JP) 1997-11-05 EP disclosed
EP-0640578-A1 Novel liquid crystalline compound having a 1,1,2,3,3,3,-hexafluoropropyl group and liquid crystal composition Chisso Corporation (JP) 1995-03-01 EP disclosed