SCHEMBL8833797

SCHEMBL8833797

COC(=O)c1cc(C(C)C=O)ccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.56
CA1 P00915 4/20 0.56
CA2 P00918 4/20 0.56
CA7 P43166 4/20 0.56
CA9 Q16790 4/20 0.56
CA14 Q9ULX7 4/20 0.56
PTGS2 P35354 2/20 0.50
MAPT P10636 1/20 0.47
LMNA P02545 1/20 0.46
TSHR P16473 1/20 0.46
PDK2 Q15119 1/20 0.44
PDK4 Q16654 1/20 0.44
ADRB2 P07550 3/20 0.43
ADRB1 P08588 3/20 0.43
ADRB3 P13945 3/20 0.43
ADRA1D P25100 3/20 0.43
ADRA1A P35348 3/20 0.43
ADRA1B P35368 3/20 0.43
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12208227 0.82 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL9755160 0.82 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL8833791 0.81 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL13359783 0.81 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL8833720 0.80 ALDH1A1 (0.42) CA12CA1CA2CA7CA9
SCHEMBL683267 0.78 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL11263513 0.78 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL11502243 0.77 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL28165577 0.76 TDP1 (0.50) PTGS2MAPTLMNATSHRADRB2
SCHEMBL11187053 0.76 TSHR (0.57) TSHRMEN1RAB9AKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5629200-A MICROORGANISM DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1997-05-13 US disclosed