Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.46 |
| ▸ | PRKCG | P05129 | 2/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RGS12 | O14924 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PRKCB | P05771 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PRKCH | P24723 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84534 | 0.73 | EGFR (0.62) | PRKCGPRKCDEGFRSRCKDM4E | |
| SCHEMBL30557775 | 0.73 | EGFR (0.62) | PRKCGPRKCDEGFRSRCKDM4E | |
| SCHEMBL20590548 | 0.72 | PDGFRB (0.46) | KDRPRKCGPRKCDEGFRSRC | |
| SCHEMBL10733814 | 0.68 | MAPT (0.68) | EGFRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9409082 | 0.68 | EGFR (0.43) | PRKCGPRKCDEGFRSRCKDM4E | |
| SCHEMBL18170485 | 0.67 | KDR (0.58) | KDRMEN1KMT2AFLT4AURKB | |
| SCHEMBL8026004 | 0.66 | HSD17B10 (0.42) | PRKCGPRKCDEGFRSRCKDM4E | |
| SCHEMBL30775189 | 0.66 | MAPK10 (0.51) | KDRPRKCGPRKCDEGFRSRC | |
| SCHEMBL30331758 | 0.65 | PARP10 (0.69) | KDRPRKCGPRKCDPRKD3DYRK1A | |
| SCHEMBL28969955 | 0.64 | MAPT (0.65) | KDM4EMEN1ALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663336-A | IMIDATION OF DIAMINOPHTHALIC ACID TO FORM KINASE INHIBITORS AS ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| US-5491144-A | KINASE INHIBITORS, ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-02-13 | — | — | US | disclosed |