Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PRKCH | P24723 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409167 | 0.72 | APP (0.40) | EGFRSRCMEN1MAPTKMT2A | |
| SCHEMBL30557775 | 0.71 | EGFR (0.62) | EGFRSRCMEN1MAPTKMT2A | |
| SCHEMBL84534 | 0.71 | EGFR (0.62) | EGFRSRCMEN1MAPTKMT2A | |
| SCHEMBL8834089 | 0.68 | KDR (0.46) | EGFRSRCMEN1MAPTKMT2A | |
| SCHEMBL10733814 | 0.66 | MAPT (0.68) | EGFRMEN1MAPTKMT2AKDM4E | |
| SCHEMBL8026004 | 0.64 | HSD17B10 (0.42) | EGFRSRCMEN1MAPTKMT2A | |
| SCHEMBL10049028 | 0.63 | PRKD3 (0.34) | KMT2APRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL28969955 | 0.62 | MAPT (0.65) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL23985252 | 0.62 | PARP1 (0.39) | MEN1MAPTKMT2ARGS12PRKD3 | |
| SCHEMBL1081094 | 0.62 | PBRM1 (0.49) | MEN1KMT2APRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | claimed |
| EP-0600832-A1 | Derivatives of diamino benzoic and diamino phthalic acid und their use as protein linase inhibitors | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |