Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10804580 | 0.85 | MAOB (0.58) | MAOAMAOBKMT2AMEN1RAB9A | |
| SCHEMBL30862482 | 0.85 | ALDH1A1 (0.57) | MAOAMAOBKMT2AMEN1RAB9A | |
| SCHEMBL18921197 | 0.85 | ALDH1A1 (0.57) | MAOAMAOBKMT2AMEN1RAB9A | |
| SCHEMBL8834965 | 0.83 | MAOB (0.58) | MAOAMAOBKMT2AMEN1RAB9A | |
| SCHEMBL8835418 | 0.83 | MAOB (0.60) | MAOAMAOBKMT2AMEN1RAB9A | |
| SCHEMBL7915768 | 0.82 | ALDH1A1 (0.58) | MAOAMAOBKMT2AMEN1RAB9A | |
| SCHEMBL8835021 | 0.81 | KMT2A (0.60) | MAOAMAOBKMT2AMEN1RAB9A | |
| SCHEMBL8834944 | 0.81 | IGLV6-57 (0.58) | KMT2AMEN1RAB9AARKDM4E | |
| SCHEMBL12617766 | 0.81 | CYP1A1 (0.60) | MAOAMAOBKMT2AMEN1RAB9A | |
| SCHEMBL12617458 | 0.81 | MAOB (0.67) | MAOAMAOBKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783537-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010049-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1996-04-04 | — | — | WO | disclosed |