Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | RARB | P10826 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28531864 | 0.92 | PLA2G4B (0.64) | PLA2G4BTP53TSHRRARBLMNA | |
| SCHEMBL8082282 | 0.85 | PLA2G4B (0.62) | PLA2G4BTP53TSHRRARBPLA2G4A | |
| SCHEMBL8414525 | 0.84 | PLA2G4B (0.68) | PLA2G4BTP53TSHRLMNAPOLB | |
| SCHEMBL9574328 | 0.84 | PLA2G4B (0.60) | PLA2G4BTP53TSHRRARBPLA2G4A | |
| SCHEMBL5471637 | 0.84 | PLA2G4B (0.60) | PLA2G4BTP53TSHRRARBLMNA | |
| SCHEMBL9741323 | 0.84 | PLA2G4B (0.71) | PLA2G4BTP53TSHRLMNAPOLB | |
| SCHEMBL11203428 | 0.83 | ABCB1 (0.64) | PLA2G4BLMNAPOLBMAPTNPSR1 | |
| SCHEMBL4799846 | 0.82 | TP53 (0.80) | PLA2G4BTP53TSHRRARBPLA2G4A | |
| SCHEMBL6071806 | 0.82 | MAPT (0.69) | PLA2G4BTP53TSHRLMNAPOLB | |
| SCHEMBL10975809 | 0.82 | PLA2G4B (0.59) | PLA2G4BTP53TSHRRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783537-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010049-A1 | CUMARIN AND QUINOLINONE DERIVATIVES FOR PREPARING LIQUID CRYSTAL ORIENTATION LAYERS | F. HOFFMANN-LA ROCHE AG (CH) | 1996-04-04 | — | — | WO | disclosed |
| US-4158011-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1979-06-12 | — | — | US | disclosed |