Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834974 | 1.00 | HTR2C (0.50) | HTR2CHDAC2ADRA2ADRD1DRD5 | |
| SCHEMBL8835534 | 0.84 | HTR2C (0.50) | HTR2CHDAC2MAOB | |
| SCHEMBL8835537 | 0.84 | HTR2C (0.50) | HTR2CHDAC2MAOB | |
| SCHEMBL28714384 | 0.83 | HTR2C (0.56) | HTR2CADRA2ADRD1DRD5ADRA1B | |
| SCHEMBL8835710 | 0.83 | HTR2C (0.49) | HTR2CHDAC2MAOB | |
| SCHEMBL8835704 | 0.83 | HTR2C (0.49) | HTR2CHDAC2MAOB | |
| SCHEMBL8963025 | 0.81 | HTR2C (0.57) | HTR2CHDAC2MAOBCNR1 | |
| SCHEMBL8963017 | 0.81 | HTR2C (0.57) | HTR2CHDAC2MAOBCNR1 | |
| SCHEMBL8835518 | 0.81 | HTR2C (0.46) | HTR2CHDAC2MAOBCNR1 | |
| SCHEMBL8835275 | 0.81 | HTR2C (0.46) | HTR2CHDAC2MAOBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5662830-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| US-5609791-A | Diene derivative | CHISSO CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| EP-0563982-B1 | Polycyclic diene derivatives | CHISSO CORP (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5449810-A | Diene derivative | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| EP-0563982-A2 | Polycyclic diene derivatives | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |