Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963025 | 1.00 | HTR2C (0.57) | HTR2CHDAC2MAOBCNR1 | |
| SCHEMBL8962960 | 0.95 | HTR2C (0.53) | HTR2CHDAC2MAOBCNR1 | |
| SCHEMBL8962904 | 0.95 | HTR2C (0.53) | HTR2CMAOB | |
| SCHEMBL8962900 | 0.95 | HTR2C (0.53) | HTR2CMAOB | |
| SCHEMBL8962970 | 0.93 | HTR2C (0.50) | HTR2CMAOBCNR1 | |
| SCHEMBL8962978 | 0.93 | HTR2C (0.50) | HTR2CMAOBCNR1 | |
| SCHEMBL9450845 | 0.89 | HTR2C (0.47) | HTR2CMAOBCNR1 | |
| SCHEMBL8963019 | 0.86 | HDAC2 (0.45) | HTR2CHDAC2MAOB | |
| SCHEMBL8963014 | 0.86 | HDAC2 (0.45) | HTR2CHDAC2MAOB | |
| SCHEMBL1847401 | 0.82 | HTR2C (0.73) | HTR2CMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559860-B1 | HALOVINYL-DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | EP | disclosed |
| US-5364556-A | Halovinyl-derivatives | HOFFMANN-LA ROCHE INC. (US) | 1994-11-15 | — | — | US | disclosed |