SCHEMBL8835009

SCHEMBL8835009

O=CC=CC1CCC(c2cc(F)c(F)c(F)c2)CC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8835005 1.00 HDAC2 (0.31) HDAC2
SCHEMBL8835279 0.83
SCHEMBL8835283 0.83
SCHEMBL7859003 0.82 CES2 (0.30)
SCHEMBL8736458 0.82 CES2 (0.30)
SCHEMBL8835620 0.82
SCHEMBL8835625 0.82
SCHEMBL8835263 0.80 USP5 (0.34) HDAC2
SCHEMBL8835259 0.80 USP5 (0.34) HDAC2
SCHEMBL8835129 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5662830-A Diene derivative CHISSO CORPORATION (JP) 1997-09-02 US disclosed
US-5609791-A Diene derivative CHISSO CORPORATION (JP) 1997-03-11 US disclosed
EP-0563982-B1 Polycyclic diene derivatives CHISSO CORP (JP) 1996-07-17 EP disclosed
US-5449810-A Diene derivative CHISSO CORPORATION (JP) 1995-09-12 US disclosed
EP-0563982-A2 Polycyclic diene derivatives Chisso Corporation (JP) 1993-10-06 EP disclosed